biogridDrugs - data quality

Dataset statistics

Number of variables	36
Number of observations	29093
Missing cells	0
Missing cells (%)	0.0%
Duplicate rows	0
Duplicate rows (%)	0.0%
Total size in memory	8.0 MiB
Average record size in memory	288.0 B

Variable types

CAT	29
NUM	7

Warnings

`Systematic Name` has a high cardinality: 879 distinct values	High cardinality
`Official Symbol` has a high cardinality: 2600 distinct values	High cardinality
`Synonyms` has a high cardinality: 2382 distinct values	High cardinality
`Author` has a high cardinality: 9304 distinct values	High cardinality
`Chemical Name` has a high cardinality: 5904 distinct values	High cardinality
`Chemical Synonyms` has a high cardinality: 2586 distinct values	High cardinality
`Chemical Brands` has a high cardinality: 1271 distinct values	High cardinality
`Chemical Source ID` has a high cardinality: 5737 distinct values	High cardinality
`Molecular Formula` has a high cardinality: 4910 distinct values	High cardinality
`ATC Codes` has a high cardinality: 1427 distinct values	High cardinality
`CAS Number` has a high cardinality: 2116 distinct values	High cardinality
`Related BioGRID Gene ID` has a high cardinality: 207 distinct values	High cardinality
`Related Entrez Gene ID` has a high cardinality: 207 distinct values	High cardinality
`Related Systematic Name` has a high cardinality: 55 distinct values	High cardinality
`Related Official Symbol` has a high cardinality: 207 distinct values	High cardinality
`Related Synonyms` has a high cardinality: 194 distinct values	High cardinality
`Notes` has a high cardinality: 387 distinct values	High cardinality
`InChIKey` has a high cardinality: 5458 distinct values	High cardinality
`Curated By` is highly correlated with `Chemical Source`	High correlation
`Chemical Source` is highly correlated with `Curated By` and 1 other fields	High correlation
`Method Description` is highly correlated with `Method` and 1 other fields	High correlation
`Method` is highly correlated with `Method Description` and 1 other fields	High correlation
`Related Organism` is highly correlated with `Related Organism ID` and 1 other fields	High correlation
`Related Organism ID` is highly correlated with `Related Organism` and 1 other fields	High correlation
`Related Type` is highly correlated with `Action` and 6 other fields	High correlation
`Action` is highly correlated with `Related Type`	High correlation
`Interaction Type` is highly correlated with `Related Type`	High correlation
`#BioGRID Chemical Interaction ID` has unique values	Unique

Reproduction

Analysis started	2020-11-18 22:51:13.646426
Analysis finished	2020-11-18 22:51:26.583626
Duration	12.94 seconds
Software version	pandas-profiling v2.9.0
Download configuration	config.yaml

#BioGRID Chemical Interaction ID
Real number (ℝ_≥0)

UNIQUE

Distinct	29093
Distinct (%)	100.0%
Missing	0
Missing (%)	0.0%
Infinite	0
Infinite (%)	0.0%

Mean	14658.87413
Minimum	1
Maximum	29833
Zeros	0
Zeros (%)	0.0%
Memory size	227.3 KiB

Quantile statistics

Minimum	1
5-th percentile	1455.6
Q1	7314
median	14612
Q3	21976
95-th percentile	27864.4
Maximum	29833
Range	29832
Interquartile range (IQR)	14662

Descriptive statistics

Standard deviation	8494.8804
Coefficient of variation (CV)	0.579504287
Kurtosis	-1.185664303
Mean	14658.87413
Median Absolute Deviation (MAD)	7331
Skewness	0.01478935383
Sum	426470625
Variance	72162993
Monotocity	Strictly increasing

Histogram with fixed size bins (bins=50)

Value	Count	Frequency (%)
2047	1	< 0.1%
19779	1	< 0.1%
27911	1	< 0.1%
5384	1	< 0.1%
7433	1	< 0.1%
1290	1	< 0.1%
3339	1	< 0.1%
13580	1	< 0.1%
15629	1	< 0.1%
9486	1	< 0.1%
Other values (29083)	29083	> 99.9%

Minimum 5 values
Maximum 5 values

Value	Count	Frequency (%)
1	1	< 0.1%
2	1	< 0.1%
3	1	< 0.1%
4	1	< 0.1%
5	1	< 0.1%

Value	Count	Frequency (%)
29833	1	< 0.1%
29832	1	< 0.1%
29831	1	< 0.1%
29830	1	< 0.1%
29829	1	< 0.1%

BioGRID Gene ID
Real number (ℝ_≥0)

Distinct	2612
Distinct (%)	9.0%
Missing	0
Missing (%)	0.0%
Infinite	0
Infinite (%)	0.0%

Mean	190842.2293
Minimum	35583
Maximum	4359045
Zeros	0
Zeros (%)	0.0%
Memory size	227.3 KiB

Quantile statistics

Minimum	35583
5-th percentile	106660
Q1	108147
median	109984
Q3	112593
95-th percentile	851212.6
Maximum	4359045
Range	4323462
Interquartile range (IQR)	4446

Descriptive statistics

Standard deviation	368885.2168
Coefficient of variation (CV)	1.932932864
Kurtosis	76.60111397
Mean	190842.2293
Median Absolute Deviation (MAD)	2271
Skewness	7.878008067
Sum	5552172976
Variance	1.360763032e+11
Monotocity	Not monotonic

Histogram with fixed size bins (bins=50)

Value	Count	Frequency (%)
108147	336	1.2%
109505	335	1.2%
108828	269	0.9%
111715	258	0.9%
106663	242	0.8%
111464	240	0.8%
106658	240	0.8%
112423	228	0.8%
119360	226	0.8%
115330	218	0.7%
Other values (2602)	26501	91.1%

Minimum 5 values
Maximum 5 values

Value	Count	Frequency (%)
35583	1	< 0.1%
36434	6	< 0.1%
37567	2	< 0.1%
37611	2	< 0.1%
38136	2	< 0.1%

Value	Count	Frequency (%)
4359045	1	< 0.1%
4352387	1	< 0.1%
4351464	1	< 0.1%
4351372	1	< 0.1%
4252304	4	< 0.1%

Entrez Gene ID
Real number (ℝ_≥0)

Distinct	2612
Distinct (%)	9.0%
Missing	0
Missing (%)	0.0%
Infinite	0
Infinite (%)	0.0%

Mean	98850.16341
Minimum	2
Maximum	13316550
Zeros	0
Zeros (%)	0.0%
Memory size	227.3 KiB

Quantile statistics

Minimum	2
5-th percentile	151
Q1	1813
median	3784
Q3	6716
95-th percentile	945514
Maximum	13316550
Range	13316548
Interquartile range (IQR)	4903

Descriptive statistics

Standard deviation	389075.0136
Coefficient of variation (CV)	3.936007794
Kurtosis	102.4079118
Mean	98850.16341
Median Absolute Deviation (MAD)	2552
Skewness	7.67624811
Sum	2875847804
Variance	1.513793662e+11
Monotocity	Not monotonic

Histogram with fixed size bins (bins=50)

Value	Count	Frequency (%)
1813	336	1.2%
3269	335	1.2%
2554	269	0.9%
5743	258	0.9%
154	242	0.8%
5468	240	0.8%
148	240	0.8%
6532	228	0.8%
51185	226	0.8%
10013	218	0.7%
Other values (2602)	26501	91.1%

Minimum 5 values
Maximum 5 values

Value	Count	Frequency (%)
2	7	< 0.1%
15	9	< 0.1%
16	5	< 0.1%
18	42	0.1%
19	15	0.1%

Value	Count	Frequency (%)
13316550	1	< 0.1%
8303012	1	< 0.1%
5651987	8	< 0.1%
3885966	4	< 0.1%
3783733	2	< 0.1%

Systematic Name
Categorical

HIGH CARDINALITY

Distinct	879
Distinct (%)	3.0%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	21426
AD-006	226
JM21	218
RP11-147L20.2	204
RP1-130E4.1	204
Other values (874)	6815

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	21426	73.6%
AD-006	226	0.8%
JM21	218	0.7%
RP11-147L20.2	204	0.7%
RP1-130E4.1	204	0.7%
RP11-542K23.6	197	0.7%
RP11-383C12.1	118	0.4%
RP11-810O3.1	113	0.4%
HIV1gp1	104	0.4%
RP1-201D17__B.1	98	0.3%
Other values (869)	6185	21.3%

Frequencies of value counts

Unique

Unique	150 ?
Unique (%)	0.5%

Histogram of lengths of the category

Length

Max length	18
Median length	1
Mean length	3.291960265
Min length	1

Official Symbol
Categorical

HIGH CARDINALITY

Distinct	2600
Distinct (%)	8.9%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

DRD2	336
HRH1	335
GABRA1	269
PTGS2	258
ADRB2	242
Other values (2595)	27653

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
DRD2	336	1.2%
HRH1	335	1.2%
GABRA1	269	0.9%
PTGS2	258	0.9%
ADRB2	242	0.8%
ADRA1A	240	0.8%
PPARG	240	0.8%
SLC6A4	228	0.8%
CRBN	226	0.8%
HDAC6	218	0.7%
Other values (2590)	26501	91.1%

Frequencies of value counts

Unique

Unique	449 ?
Unique (%)	1.5%

Histogram of lengths of the category

Length

Max length	10
Median length	5
Mean length	4.810126147
Min length	2

Synonyms
Categorical

HIGH CARDINALITY

Distinct	2382
Distinct (%)	8.2%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	2780
D2DR\|D2R	336
H1-R\|hisH1	335
ECA4\|EIEE19\|EJM\|EJM5	269
COX-2\|COX2\|GRIPGHS\|PGG/HS\|PGHS-2\|PHS-2\|hCox-2	258
Other values (2377)	25115

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	2780	9.6%
D2DR\|D2R	336	1.2%
H1-R\|hisH1	335	1.2%
ECA4\|EIEE19\|EJM\|EJM5	269	0.9%
COX-2\|COX2\|GRIPGHS\|PGG/HS\|PGHS-2\|PHS-2\|hCox-2	258	0.9%
ADRB2R\|ADRBR\|B2AR\|BAR\|BETA2AR	242	0.8%
CIMT1\|GLM1\|NR1C3\|PPARG1\|PPARG2\|PPARgamma	240	0.8%
ADRA1C\|ADRA1L1\|ALPHA1AAR	240	0.8%
5-HTT\|5-HTTLPR\|5HTT\|HTT\|OCD1\|SERT\|SERT1\|hSERT	228	0.8%
MRT2\|MRT2A	226	0.8%
Other values (2372)	23939	82.3%

Frequencies of value counts

Unique

Unique	419 ?
Unique (%)	1.4%

Histogram of lengths of the category

Length

Max length	202
Median length	18
Mean length	21.18997697
Min length	1

Organism ID
Real number (ℝ_≥0)

Distinct	21
Distinct (%)	0.1%
Missing	0
Missing (%)	0.0%
Infinite	0
Infinite (%)	0.0%

Mean	40178.96532
Minimum	6239
Maximum	559292
Zeros	0
Zeros (%)	0.0%
Memory size	227.3 KiB

Quantile statistics

Minimum	6239
5-th percentile	9606
Q1	9606
median	9606
Q3	9606
95-th percentile	511145
Maximum	559292
Range	553053
Interquartile range (IQR)	0

Descriptive statistics

Standard deviation	116246.8037
Coefficient of variation (CV)	2.893225417
Kurtosis	11.91874677
Mean	40178.96532
Median Absolute Deviation (MAD)	0
Skewness	3.693549268
Sum	1168926638
Variance	1.351331937e+10
Monotocity	Not monotonic

Histogram with fixed size bins (bins=21)

Value	Count	Frequency (%)
9606	26841	92.3%
511145	1590	5.5%
224308	164	0.6%
237561	108	0.4%
11676	105	0.4%
171101	82	0.3%
10298	65	0.2%
170187	61	0.2%
10245	21	0.1%
10376	10	< 0.1%
Other values (11)	46	0.2%

Minimum 5 values
Maximum 5 values

Value	Count	Frequency (%)
6239	8	< 0.1%
9606	26841	92.3%
10090	2	< 0.1%
10116	2	< 0.1%
10245	21	0.1%

Value	Count	Frequency (%)
559292	7	< 0.1%
511145	1590	5.5%
347515	8	< 0.1%
272634	2	< 0.1%
269084	4	< 0.1%

Organism
Categorical

Distinct	18
Distinct (%)	0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

Homo sapiens	26841
Escherichia coli	1595
Bacillus subtilis	164
Streptococcus pneumoniae	143
Candida albicans	108
Other values (13)	242

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
Homo sapiens	26841	92.3%
Escherichia coli	1595	5.5%
Bacillus subtilis	164	0.6%
Streptococcus pneumoniae	143	0.5%
Candida albicans	108	0.4%
Human Immunodeficiency Virus 1	105	0.4%
Human Herpesvirus 1	65	0.2%
Vaccinia Virus	21	0.1%
Human Herpesvirus 4	10	< 0.1%
Leishmania major	8	< 0.1%
Other values (8)	33	0.1%

Frequencies of value counts

Unique

Unique	0 ?
Unique (%)	0.0%

Histogram of lengths of the category

Length

Max length	30
Median length	12
Mean length	12.41814182
Min length	12

Action
Categorical

HIGH CORRELATION

Distinct	35
Distinct (%)	0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

unknown	12914
inhibitor	5353
antagonist	3954
agonist	3116
potentiator	870
Other values (30)	2886

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
unknown	12914	44.4%
inhibitor	5353	18.4%
antagonist	3954	13.6%
agonist	3116	10.7%
potentiator	870	3.0%
binder	411	1.4%
cofactor	391	1.3%
degradation	369	1.3%
positive allosteric modulator	289	1.0%
inducer	209	0.7%
Other values (25)	1217	4.2%

Frequencies of value counts

Unique

Unique	3 ?
Unique (%)	< 0.1%

Histogram of lengths of the category

Length

Max length	31
Median length	7
Mean length	8.381535077
Min length	6

Interaction Type
Categorical

HIGH CORRELATION

Distinct	5
Distinct (%)	< 0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

target	28724
recruited e3 ligase	199
recruited E3 ligase	167
lysosome-targeting protein	2
autophagy-targeting protein	1

Frequencies
Length

Value	Count	Frequency (%)
target	28724	98.7%
recruited e3 ligase	199	0.7%
recruited E3 ligase	167	0.6%
lysosome-targeting protein	2	< 0.1%
autophagy-targeting protein	1	< 0.1%

Frequencies of value counts

Unique

Unique	1 ?
Unique (%)	< 0.1%

Histogram of lengths of the category

Length

Max length	27
Median length	6
Mean length	6.16564122
Min length	6

Author
Categorical

HIGH CARDINALITY

Distinct	9304
Distinct (%)	32.0%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

Berman HM (2000)	3966
Imming P (2006)	3480
Overington JP (2006)	3455
Chen X (2002)	1032
Riss J (2008)	251
Other values (9299)	16909

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
Berman HM (2000)	3966	13.6%
Imming P (2006)	3480	12.0%
Overington JP (2006)	3455	11.9%
Chen X (2002)	1032	3.5%
Riss J (2008)	251	0.9%
Moehler H (2002)	183	0.6%
Yamakura T (2001)	165	0.6%
Mehta AK (1999)	110	0.4%
Nasrallah HA (2008)	109	0.4%
Kvernmo T (2008)	100	0.3%
Other values (9294)	16242	55.8%

Frequencies of value counts

Unique

Unique	6696 ?
Unique (%)	23.0%

Histogram of lengths of the category

Length

Max length	36
Median length	16
Mean length	16.32097068
Min length	11

Pubmed ID
Real number (ℝ_≥0)

Distinct	9532
Distinct (%)	32.8%
Missing	0
Missing (%)	0.0%
Infinite	0
Infinite (%)	0.0%

Mean	14267905.68
Minimum	10722
Maximum	32840532
Zeros	0
Zeros (%)	0.0%
Memory size	227.3 KiB

Quantile statistics

Minimum	10722
5-th percentile	4402328.8
Q1	10592235
median	15939622
Q3	17139284
95-th percentile	20810709.4
Maximum	32840532
Range	32829810
Interquartile range (IQR)	6547049

Descriptive statistics

Standard deviation	5080699.196
Coefficient of variation (CV)	0.35609285
Kurtosis	1.014743907
Mean	14267905.68
Median Absolute Deviation (MAD)	3497863
Skewness	-0.04868991935
Sum	4.150961799e+11
Variance	2.581350432e+13
Monotocity	Not monotonic

Histogram with fixed size bins (bins=50)

Value	Count	Frequency (%)
10592235	3966	13.6%
17016423	3480	12.0%
17139284	3455	11.9%
11752352	1032	3.5%
18384456	251	0.9%
11752090	183	0.6%
11264449	164	0.6%
10209232	110	0.4%
17848919	109	0.4%
18691132	100	0.3%
Other values (9522)	16243	55.8%

Minimum 5 values
Maximum 5 values

Value	Count	Frequency (%)
10722	9	< 0.1%
11134	1	< 0.1%
16716	2	< 0.1%
17374	1	< 0.1%
18565	2	< 0.1%

Value	Count	Frequency (%)
32840532	1	< 0.1%
32803978	1	< 0.1%
32778845	1	< 0.1%
32750566	1	< 0.1%
32728216	2	< 0.1%

BioGRID Publication ID
Real number (ℝ_≥0)

Distinct	9532
Distinct (%)	32.8%
Missing	0
Missing (%)	0.0%
Infinite	0
Infinite (%)	0.0%

Mean	176055.8821
Minimum	283
Maximum	224925
Zeros	0
Zeros (%)	0.0%
Memory size	227.3 KiB

Quantile statistics

Minimum	283
5-th percentile	171741
Q1	171742
median	173938
Q3	178445
95-th percentile	188559.4
Maximum	224925
Range	224642
Interquartile range (IQR)	6703

Descriptive statistics

Standard deviation	14019.82986
Coefficient of variation (CV)	0.07963283983
Kurtosis	50.17064479
Mean	176055.8821
Median Absolute Deviation (MAD)	2197
Skewness	-3.403223845
Sum	5121993777
Variance	196555629.2
Monotocity	Not monotonic

Histogram with fixed size bins (bins=50)

Value	Count	Frequency (%)
172122	3966	13.6%
171742	3480	12.0%
171741	3455	11.9%
171740	1032	3.5%
174202	251	0.9%
174537	183	0.6%
174568	164	0.6%
174569	110	0.4%
174616	109	0.4%
174662	100	0.3%
Other values (9522)	16243	55.8%

Minimum 5 values
Maximum 5 values

Value	Count	Frequency (%)
283	1	< 0.1%
447	1	< 0.1%
744	1	< 0.1%
1039	2	< 0.1%
1042	2	< 0.1%

Value	Count	Frequency (%)
224925	1	< 0.1%
224924	1	< 0.1%
224923	2	< 0.1%
224922	2	< 0.1%
224921	2	< 0.1%

BioGRID Chemical ID
Real number (ℝ_≥0)

Distinct	5904
Distinct (%)	20.3%
Missing	0
Missing (%)	0.0%
Infinite	0
Infinite (%)	0.0%

Mean	2239.205479
Minimum	1
Maximum	9750
Zeros	0
Zeros (%)	0.0%
Memory size	227.3 KiB

Quantile statistics

Minimum	1
5-th percentile	109
Q1	455
median	1142
Q3	3362
95-th percentile	7819
Maximum	9750
Range	9749
Interquartile range (IQR)	2907

Descriptive statistics

Standard deviation	2474.590449
Coefficient of variation (CV)	1.105119861
Kurtosis	0.8621257859
Mean	2239.205479
Median Absolute Deviation (MAD)	933
Skewness	1.374466314
Sum	65145205
Variance	6123597.889
Monotocity	Not monotonic

Histogram with fixed size bins (bins=50)

Value	Count	Frequency (%)
151	413	1.4%
109	234	0.8%
136	211	0.7%
899	204	0.7%
137	142	0.5%
1038	129	0.4%
664	112	0.4%
326	101	0.3%
888	97	0.3%
139	96	0.3%
Other values (5894)	27354	94.0%

Minimum 5 values
Maximum 5 values

Value	Count	Frequency (%)
1	6	< 0.1%
2	28	0.1%
4	15	0.1%
5	36	0.1%
6	6	< 0.1%

Value	Count	Frequency (%)
9750	1	< 0.1%
9749	1	< 0.1%
9748	1	< 0.1%
9747	1	< 0.1%
9746	1	< 0.1%

Chemical Name
Categorical

HIGH CARDINALITY

Distinct	5904
Distinct (%)	20.3%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

NADH	413
Pyridoxal Phosphate	234
L-Glutamic Acid	211
Zonisamide	204
Glutathione	142
Other values (5899)	27889

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
NADH	413	1.4%
Pyridoxal Phosphate	234	0.8%
L-Glutamic Acid	211	0.7%
Zonisamide	204	0.7%
Glutathione	142	0.5%
Ergoloid mesylate	129	0.4%
Galantamine	112	0.4%
Olanzapine	101	0.3%
Ethanol	97	0.3%
Glycine	96	0.3%
Other values (5894)	27354	94.0%

Frequencies of value counts

Unique

Unique	2503 ?
Unique (%)	8.6%

Histogram of lengths of the category

Length

Max length	874
Median length	12
Mean length	22.17474994
Min length	3

Chemical Synonyms
Categorical

HIGH CARDINALITY

Distinct	2586
Distinct (%)	8.9%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	8236
DPNH\|Reduced nicotinamide adenine diphosphate\|Nicotinamide-adenine dinucleotide, reduced\|1,4-dihydronicotinamide adenine dinucleotide\|Reduced nicotinamide-adenine dinucleotide\|NAD reduced form\|Nicotinamide adenine dinucleotide (reduced)	413
Pyridoxal 5-monophosphoric acid ester\|PLP\|Pyridoxal phosphate anhydrous\|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde\|Pyridoxal 5-phosphate\|Pyridoxal-P\|Pyridoxal 5'-phosphate\|Pyridoxal P\|Codecarboxylase\|Pyridoxal-5P\|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	234
(S)-Glutamic acid\|(2S)-2-Aminopentanedioic acid\|L-Glutamate\|Glutamic acid\|(S)-2-Aminopentanedioic acid\|L-Glutaminic acid\|Glu	211
1,2-Benzisoxazole-3-methanesulfonamide\|Zonisamida\|Zonisamidum\|Benzo[D]isoxazol-3-yl-methanesulfonamide\|3-(Sulfamoylmethyl)-1,2-benzisoxazole	204
Other values (2581)	19795

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	8236	28.3%
DPNH\|Reduced nicotinamide adenine diphosphate\|Nicotinamide-adenine dinucleotide, reduced\|1,4-dihydronicotinamide adenine dinucleotide\|Reduced nicotinamide-adenine dinucleotide\|NAD reduced form\|Nicotinamide adenine dinucleotide (reduced)	413	1.4%
Pyridoxal 5-monophosphoric acid ester\|PLP\|Pyridoxal phosphate anhydrous\|3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyde\|Pyridoxal 5-phosphate\|Pyridoxal-P\|Pyridoxal 5'-phosphate\|Pyridoxal P\|Codecarboxylase\|Pyridoxal-5P\|3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate	234	0.8%
(S)-Glutamic acid\|(2S)-2-Aminopentanedioic acid\|L-Glutamate\|Glutamic acid\|(S)-2-Aminopentanedioic acid\|L-Glutaminic acid\|Glu	211	0.7%
1,2-Benzisoxazole-3-methanesulfonamide\|Zonisamida\|Zonisamidum\|Benzo[D]isoxazol-3-yl-methanesulfonamide\|3-(Sulfamoylmethyl)-1,2-benzisoxazole	204	0.7%
Glutathione-SH\|Glutathione\|5-L-Glutamyl-L-cysteinylglycine\|N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine\|gamma-L-Glutamyl-L-cysteinyl-glycine\|Reduced glutathione\|GSH	142	0.5%
Dihydroergotoxine Methanesulfonate\|codergocrine mesylate\|dihydroergotoxine monomethanesulfonate\|Dihydroergotoxine Mesylate\|co-dergocrine mesilate\|dihydroergotoxine methanesulfonate\|co-dergocrine mesylate\|ergoloid methanesulfonate\|Ergoloid Mesylates\|co-dergocrine methanesulfonate\|ergoloid methanesulfonates\|Dihydroergotoxine Mesilate\|codergocrine methanesulfonate\|codergocrine mesilate\|dihydrogenated ergot alkaloids\|dihydroergotoxine methanesulfonates\|hydrogenated ergot alkaloids	129	0.4%
Galanthamine\|(-)-Galanthamine	112	0.4%
Olanzapinum\|2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine\|Olanzapin\|Olanzapine\|Zyprexa\|Olanzapina	101	0.3%
thanol\|Methylcarbinol\|Ethyl Alcohol\|Alcohol\|Alcohol etlico\|thylalkohol\|Grain alcohol\|Alcohol (ethyl)\|1-Hydroxyethane\|Alcohol anhydrous\|thanol\|Alcohol, denatured\|etanol\|Dehydrated ethanol\|Spiritus vini\|Hydroxyethane\|Alkohol\|Alcool thylique\|Alcohol denatured	97	0.3%
Other values (2576)	19214	66.0%

Frequencies of value counts

Unique

Unique	889 ?
Unique (%)	3.1%

Histogram of lengths of the category

Length

Max length	3645
Median length	77
Mean length	134.6815041
Min length	1

Chemical Brands
Categorical

HIGH CARDINALITY

Distinct	1271
Distinct (%)	4.4%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	13620
primene 10%\|aminosyn ii 5% inj	283
freamine iii\|primene 10%\|2.5%	211
zonegran\|zonisamide	204
2.5% travasol amino acid injec	159
Other values (1266)	14616

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	13620	46.8%
primene 10%\|aminosyn ii 5% inj	283	1.0%
freamine iii\|primene 10%\|2.5%	211	0.7%
zonegran\|zonisamide	204	0.7%
2.5% travasol amino acid injec	159	0.5%
amo endosol extra\|bss plus\|nav	142	0.5%
hydergine tablets, 1mg	129	0.4%
reminyl -(12mg)\|pms-galantam	112	0.4%
olanzapine and fluoxetine\|sand	101	0.3%
lisa frank bubblegum antisepti	97	0.3%
Other values (1261)	14035	48.2%

Frequencies of value counts

Unique

Unique	112 ?
Unique (%)	0.4%

Histogram of lengths of the category

Length

Max length	30
Median length	7
Mean length	14.30072526
Min length	1

Chemical Source
Categorical

HIGH CORRELATION

Distinct	7
Distinct (%)	< 0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

DRUGBANK	27904
PUBCHEM	575
BIOGRID	369
CHEMSPIDER	206
CHEMBL	36
Other values (2)	3

Frequencies
Length

Value	Count	Frequency (%)
DRUGBANK	27904	95.9%
PUBCHEM	575	2.0%
BIOGRID	369	1.3%
CHEMSPIDER	206	0.7%
CHEMBL	36	0.1%
CHEBI	2	< 0.1%
PDB	1	< 0.1%

Frequencies of value counts

Unique

Unique	1 ?
Unique (%)	< 0.1%

Histogram of lengths of the category

Length

Max length	10
Median length	8
Mean length	7.978860894
Min length	3

Chemical Source ID
Categorical

HIGH CARDINALITY

Distinct	5737
Distinct (%)	19.7%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

DB00157	413
-	369
DB00114	234
DB00142	211
DB00909	204
Other values (5732)	27662

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
DB00157	413	1.4%
-	369	1.3%
DB00114	234	0.8%
DB00142	211	0.7%
DB00909	204	0.7%
DB00143	142	0.5%
DB01049	129	0.4%
DB00674	112	0.4%
DB00334	101	0.3%
DB00898	97	0.3%
Other values (5727)	27081	93.1%

Frequencies of value counts

Unique

Unique	2375 ?
Unique (%)	8.2%

Histogram of lengths of the category

Length

Max length	13
Median length	7
Mean length	6.956450005
Min length	1

Molecular Formula
Categorical

HIGH CARDINALITY

Distinct	4910
Distinct (%)	16.9%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	846
C21H29N7O14P2	413
C8H10NO6P	234
C5H9NO4	216
C8H8N2O3S	205
Other values (4905)	27179

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	846	2.9%
C21H29N7O14P2	413	1.4%
C8H10NO6P	234	0.8%
C5H9NO4	216	0.7%
C8H8N2O3S	205	0.7%
C17H21NO3	146	0.5%
C10H17N3O6S	142	0.5%
C30H41N5O8S	129	0.4%
C17H20N4S	101	0.3%
C2H5NO2	100	0.3%
Other values (4900)	26561	91.3%

Frequencies of value counts

Unique

Unique	1867 ?
Unique (%)	6.4%

Histogram of lengths of the category

Length

Max length	149
Median length	10
Mean length	9.997972021
Min length	1

Chemical Type
Categorical

Distinct	3
Distinct (%)	< 0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

small molecule	27480
biologic	1596
polypeptidic	17

Frequencies
Length

Value	Count	Frequency (%)
small molecule	27480	94.5%
biologic	1596	5.5%
polypeptidic	17	0.1%

Frequencies of value counts

Unique

Unique	0 ?
Unique (%)	0.0%

Histogram of lengths of the category

Length

Max length	14
Median length	14
Mean length	13.66967999
Min length	8

ATC Codes
Categorical

HIGH CARDINALITY

Distinct	1427
Distinct (%)	4.9%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	12905
A11HA06	234
N03AX15	204
V03AB32	142
C04AE51\|C04AE01	129
Other values (1422)	15479

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	12905	44.4%
A11HA06	234	0.8%
N03AX15	204	0.7%
V03AB32	142	0.5%
C04AE51\|C04AE01	129	0.4%
N06DA04	112	0.4%
N05AH03	101	0.3%
D08AX08\|V03AB16\|V03AZ01	97	0.3%
B05CX03	96	0.3%
N06BC01\|V04CG30	75	0.3%
Other values (1417)	14998	51.6%

Frequencies of value counts

Unique

Unique	134 ?
Unique (%)	0.5%

Histogram of lengths of the category

Length

Max length	303
Median length	7
Mean length	7.548104355
Min length	1

CAS Number
Categorical

HIGH CARDINALITY

Distinct	2116
Distinct (%)	7.3%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	7655
58-68-4	413
54-47-7	234
56-86-0	211
68291-97-4	204
Other values (2111)	20376

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	7655	26.3%
58-68-4	413	1.4%
54-47-7	234	0.8%
56-86-0	211	0.7%
68291-97-4	204	0.7%
70-18-8	142	0.5%
8067-24-1	129	0.4%
357-70-0	112	0.4%
132539-06-1	101	0.3%
64-17-5	97	0.3%
Other values (2106)	19795	68.0%

Frequencies of value counts

Unique

Unique	244 ?
Unique (%)	0.8%

Histogram of lengths of the category

Length

Max length	12
Median length	8
Mean length	6.882205341
Min length	1

Curated By
Categorical

HIGH CORRELATION

Distinct	3
Distinct (%)	< 0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

DRUGBANK	27785
BINDINGDB	714
BIOGRID	594

Frequencies
Length

Value	Count	Frequency (%)
DRUGBANK	27785	95.5%
BINDINGDB	714	2.5%
BIOGRID	594	2.0%

Frequencies of value counts

Unique

Unique	0 ?
Unique (%)	0.0%

Histogram of lengths of the category

Length

Max length	9
Median length	8
Mean length	8.004124704
Min length	7

Method
Categorical

HIGH CORRELATION

Distinct	8
Distinct (%)	< 0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28724
PROTAC	321
Molecular Glue	18
HaloPROTAC	15
SNIPER	9
Other values (3)	6

Frequencies
Length

Value	Count	Frequency (%)
-	28724	98.7%
PROTAC	321	1.1%
Molecular Glue	18	0.1%
HaloPROTAC	15	0.1%
SNIPER	9	< 0.1%
CLIPTAC	3	< 0.1%
LYTAC	2	< 0.1%
ATTEC	1	< 0.1%

Frequencies of value counts

Unique

Unique	1 ?
Unique (%)	< 0.1%

Histogram of lengths of the category

Length

Max length	14
Median length	1
Mean length	1.070429313
Min length	1

Method Description
Categorical

HIGH CORRELATION

Distinct	8
Distinct (%)	< 0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28724
Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	321
Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	18
PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	15
Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	9
Other values (3)	6

Frequencies
Length

Value	Count	Frequency (%)
-	28724	98.7%
Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	321	1.1%
Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	18	0.1%
PROTAC variant that induces degradation of HaloTag fusion proteins; structured as E3 binding moiety--linker--HaloTag binding moiety; target degraded via UPS	15	0.1%
Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	9	< 0.1%
PROTAC variant formed in cells by click chemistry; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	3	< 0.1%
Lysosome Targeting Chimera; structured as glycopeptide ligand--linker--target binding moiety; target degraded via endosome-lysosome system	2	< 0.1%
Autophagosome Tethering Compound; structured as a LC3 binding moiety--linker--target binding moiety; target degraded via autophagic degradation	1	< 0.1%

Frequencies of value counts

Unique

Unique	1 ?
Unique (%)	< 0.1%

Histogram of lengths of the category

Length

Max length	213
Median length	1
Mean length	2.582717492
Min length	1

Related BioGRID Gene ID
Categorical

HIGH CARDINALITY

Distinct	207
Distinct (%)	0.7%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28724
117036	26
106543	12
107160	11
108403	10
Other values (202)	310

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	28724	98.7%
117036	26	0.1%
106543	12	< 0.1%
107160	11	< 0.1%
108403	10	< 0.1%
107456	9	< 0.1%
107773	8	< 0.1%
106862	7	< 0.1%
107454	7	< 0.1%
111973	5	< 0.1%
Other values (197)	274	0.9%

Frequencies of value counts

Unique

Unique	150 ?
Unique (%)	0.5%

Histogram of lengths of the category

Length

Max length	7
Median length	1
Mean length	1.063451689
Min length	1

Related Entrez Gene ID
Categorical

HIGH CARDINALITY

Distinct	207
Distinct (%)	0.7%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28724
23476	26
25	12
695	11
2099	10
Other values (202)	310

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	28724	98.7%
23476	26	0.1%
25	12	< 0.1%
695	11	< 0.1%
2099	10	< 0.1%
1021	9	< 0.1%
1382	8	< 0.1%
367	7	< 0.1%
1019	7	< 0.1%
8019	5	< 0.1%
Other values (197)	274	0.9%

Frequencies of value counts

Unique

Unique	150 ?
Unique (%)	0.5%

Histogram of lengths of the category

Length

Max length	9
Median length	1
Mean length	1.04062833
Min length	1

Related Systematic Name
Categorical

HIGH CARDINALITY

Distinct	55
Distinct (%)	0.2%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28962
RP11-83J21.1	12
RP1-164F3.2	11
RP1-130E4.1	10
RP11-66D17.4	8
Other values (50)	90

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	28962	99.5%
RP11-83J21.1	12	< 0.1%
RP1-164F3.2	11	< 0.1%
RP1-130E4.1	10	< 0.1%
RP11-66D17.4	8	< 0.1%
RP11-383C12.1	7	< 0.1%
RP11-94L15.2	5	< 0.1%
RP11-374P20.3	5	< 0.1%
tcag7.1178	5	< 0.1%
DADB-17J1.3	5	< 0.1%
Other values (45)	63	0.2%

Frequencies of value counts

Unique

Unique	35 ?
Unique (%)	0.1%

Histogram of lengths of the category

Length

Max length	23
Median length	1
Mean length	1.046712268
Min length	1

Related Official Symbol
Categorical

HIGH CARDINALITY

Distinct	207
Distinct (%)	0.7%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28724
BRD4	26
ABL1	12
BTK	11
ESR1	10
Other values (202)	310

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	28724	98.7%
BRD4	26	0.1%
ABL1	12	< 0.1%
BTK	11	< 0.1%
ESR1	10	< 0.1%
CDK6	9	< 0.1%
CRABP2	8	< 0.1%
AR	7	< 0.1%
CDK4	7	< 0.1%
IKZF1	5	< 0.1%
Other values (197)	274	0.9%

Frequencies of value counts

Unique

Unique	150 ?
Unique (%)	0.5%

Histogram of lengths of the category

Length

Max length	8
Median length	1
Mean length	1.046402915
Min length	1

Related Synonyms
Categorical

HIGH CARDINALITY

Distinct	194
Distinct (%)	0.7%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28740
CAP\|HUNK1\|HUNKI\|MCAP	26
ABL\|JTK7\|bcr/abl\|c-ABL\|c-ABL1\|p150\|v-abl	12
AGMX1\|AT\|ATK\|BPK\|IMD1\|PSCTK1\|XLA	11
ER\|ESR\|ESRA\|ESTRR\|Era\|NR3A1	10
Other values (189)	294

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	28740	98.8%
CAP\|HUNK1\|HUNKI\|MCAP	26	0.1%
ABL\|JTK7\|bcr/abl\|c-ABL\|c-ABL1\|p150\|v-abl	12	< 0.1%
AGMX1\|AT\|ATK\|BPK\|IMD1\|PSCTK1\|XLA	11	< 0.1%
ER\|ESR\|ESRA\|ESTRR\|Era\|NR3A1	10	< 0.1%
MCPH12\|PLSTIRE	9	< 0.1%
CRABP-II\|RBP6	8	< 0.1%
AIS\|DHTR\|HUMARA\|HYSP1\|KD\|NR3C4\|SBMA\|SMAX1\|TFM	7	< 0.1%
CMM3\|PSK-J3	7	< 0.1%
ORFX\|RING3L	5	< 0.1%
Other values (184)	258	0.9%

Frequencies of value counts

Unique

Unique	139 ?
Unique (%)	0.5%

Histogram of lengths of the category

Length

Max length	76
Median length	1
Mean length	1.288557385
Min length	1

Related Organism ID
Categorical

HIGH CORRELATION

Distinct	4
Distinct (%)	< 0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28724
9606	366
10090	2
11103	1

Frequencies
Length

Value	Count	Frequency (%)
-	28724	98.7%
9606	366	1.3%
10090	2	< 0.1%
11103	1	< 0.1%

Frequencies of value counts

Unique

Unique	1 ?
Unique (%)	< 0.1%

Histogram of lengths of the category

Length

Max length	5
Median length	1
Mean length	1.038153508
Min length	1

Related Organism
Categorical

HIGH CORRELATION

Distinct	4
Distinct (%)	< 0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28724
Homo sapiens	366
Mus musculus	2
Hepatitus C Virus	1

Frequencies
Length

Value	Count	Frequency (%)
-	28724	98.7%
Homo sapiens	366	1.3%
Mus musculus	2	< 0.1%
Hepatitus C Virus	1	< 0.1%

Frequencies of value counts

Unique

Unique	1 ?
Unique (%)	< 0.1%

Histogram of lengths of the category

Length

Max length	17
Median length	1
Mean length	1.13968996
Min length	1

Related Type
Categorical

HIGH CORRELATION

Distinct	2
Distinct (%)	< 0.1%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28724
target	369

Frequencies
Length

Value	Count	Frequency (%)
-	28724	98.7%
target	369	1.3%

Frequencies of value counts

Unique

Unique	0 ?
Unique (%)	0.0%

Histogram of lengths of the category

Length

Max length	6
Median length	1
Mean length	1.063417317
Min length	1

Notes
Categorical

HIGH CARDINALITY

Distinct	387
Distinct (%)	1.3%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	28700
Standardized BVL Name: SNIPER(CRABP)-11(IAP pan-ligand:MV1 --- CRABP-II:ATRA)	3
Standardized BVL Name: ARV-825(CRBN:pomalidomide --- BRD4:OTX015)	2
Positive hit in high screen assay validated by IC-50 determination.	2
Standardized BVL Name: compound MZ1(VHL:VHL-1 --- BRD4:JQ1)	2
Other values (382)	384

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	28700	98.6%
Standardized BVL Name: SNIPER(CRABP)-11(IAP pan-ligand:MV1 --- CRABP-II:ATRA)	3	< 0.1%
Standardized BVL Name: ARV-825(CRBN:pomalidomide --- BRD4:OTX015)	2	< 0.1%
Positive hit in high screen assay validated by IC-50 determination.	2	< 0.1%
Standardized BVL Name: compound MZ1(VHL:VHL-1 --- BRD4:JQ1)	2	< 0.1%
Standardized BVL Name: dBET1(CRBN:thalidomide --- BRD4:JQ1)	2	< 0.1%
PpIX ablates TAp73/MDM2, TAp73/MDMX and TAp73/Itch complexes	2	< 0.1%
Standardized BVL Name: XZ9002 (VHL:VH032 --- HDAC3:SR-3558)	1	< 0.1%
Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- MT1HL1:foretinib)	1	< 0.1%
Standardized BVL Name: BSJ03204 (CRBN:thalidomide --- CDK4:palbociclib)	1	< 0.1%
Other values (377)	377	1.3%

Frequencies of value counts

Unique

Unique	380 ?
Unique (%)	1.3%

Histogram of lengths of the category

Length

Max length	183
Median length	1
Mean length	1.987213419
Min length	1

InChIKey
Categorical

HIGH CARDINALITY

Distinct	5458
Distinct (%)	18.8%
Missing	0
Missing (%)	0.0%
Memory size	227.3 KiB

-	2351
BOPGDPNILDQYTO-NNYOXOHSSA-N	413
NGVDGCNFYWLIFO-UHFFFAOYSA-N	234
WHUUTDBJXJRKMK-VKHMYHEASA-N	211
UBQNRHZMVUUOMG-UHFFFAOYSA-N	204
Other values (5453)	25680

Frequencies
Length

Common Values
Overview

Value	Count	Frequency (%)
-	2351	8.1%
BOPGDPNILDQYTO-NNYOXOHSSA-N	413	1.4%
NGVDGCNFYWLIFO-UHFFFAOYSA-N	234	0.8%
WHUUTDBJXJRKMK-VKHMYHEASA-N	211	0.7%
UBQNRHZMVUUOMG-UHFFFAOYSA-N	204	0.7%
RWSXRVCMGQZWBV-WDSKDSINSA-N	142	0.5%
FQHMMOGHDWAXDI-WUQHHHCFSA-N	129	0.4%
ASUTZQLVASHGKV-JDFRZJQESA-N	112	0.4%
KVWDHTXUZHCGIO-UHFFFAOYSA-N	101	0.3%
LFQSCWFLJHTTHZ-UHFFFAOYSA-N	97	0.3%
Other values (5448)	25099	86.3%

Frequencies of value counts

Unique

Unique	2312 ?
Unique (%)	7.9%

Histogram of lengths of the category

Length

Max length	36
Median length	27
Mean length	24.91070017
Min length	1

Pearson's r

The Pearson's correlation coefficient (r) is a measure of linear correlation between two variables. It's value lies between -1 and +1, -1 indicating total negative linear correlation, 0 indicating no linear correlation and 1 indicating total positive linear correlation. Furthermore, r is invariant under separate changes in location and scale of the two variables, implying that for a linear function the angle to the x-axis does not affect r.

To calculate r for two variables X and Y, one divides the covariance of X and Y by the product of their standard deviations.

Spearman's ρ

The Spearman's rank correlation coefficient (ρ) is a measure of monotonic correlation between two variables, and is therefore better in catching nonlinear monotonic correlations than Pearson's r. It's value lies between -1 and +1, -1 indicating total negative monotonic correlation, 0 indicating no monotonic correlation and 1 indicating total positive monotonic correlation.

To calculate ρ for two variables X and Y, one divides the covariance of the rank variables of X and Y by the product of their standard deviations.

Kendall's τ

Similarly to Spearman's rank correlation coefficient, the Kendall rank correlation coefficient (τ) measures ordinal association between two variables. It's value lies between -1 and +1, -1 indicating total negative correlation, 0 indicating no correlation and 1 indicating total positive correlation.

To calculate τ for two variables X and Y, one determines the number of concordant and discordant pairs of observations. τ is given by the number of concordant pairs minus the discordant pairs divided by the total number of pairs.

Phik (φk)

Phik (φk) is a new and practical correlation coefficient that works consistently between categorical, ordinal and interval variables, captures non-linear dependency and reverts to the Pearson correlation coefficient in case of a bivariate normal input distribution. There is extensive documentation available here.

Cramér's V (φc)

Cramér's V is an association measure for nominal random variables. The coefficient ranges from 0 to 1, with 0 indicating independence and 1 indicating perfect association. The empirical estimators used for Cramér's V have been proved to be biased, even for large samples. We use a bias-corrected measure that has been proposed by Bergsma in 2013 that can be found here.

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Matrix

First rows

	#BioGRID Chemical Interaction ID	BioGRID Gene ID	Entrez Gene ID	Systematic Name	Official Symbol	Synonyms	Organism ID	Organism	Action	Interaction Type	Author	Pubmed ID	BioGRID Publication ID	BioGRID Chemical ID	Chemical Name	Chemical Synonyms	Chemical Brands	Chemical Source	Chemical Source ID	Molecular Formula	Chemical Type	ATC Codes	CAS Number	Curated By	Method	Method Description	Related BioGRID Gene ID	Related Entrez Gene ID	Related Systematic Name	Related Official Symbol	Related Synonyms	Related Organism ID	Related Organism	Related Type	Notes	InChIKey
0	1	108447	2147	-	F2	PT\|RPRGL2\|THPH1	9606	Homo sapiens	inhibitor	target	Eriksson BI (2000)	11055889	171739	1	Lepirudin	Lepirudin recombinant\|Hirudin variant-1	refludan	DRUGBANK	DB00001	C287H440N80O110S6	biologic	B01AE02	138068-37-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
1	2	108447	2147	-	F2	PT\|RPRGL2\|THPH1	9606	Homo sapiens	inhibitor	target	Warkentin TE (2000)	10912644	171738	1	Lepirudin	Lepirudin recombinant\|Hirudin variant-1	refludan	DRUGBANK	DB00001	C287H440N80O110S6	biologic	B01AE02	138068-37-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
2	3	108447	2147	-	F2	PT\|RPRGL2\|THPH1	9606	Homo sapiens	inhibitor	target	Szaba FM (2002)	11807012	171737	1	Lepirudin	Lepirudin recombinant\|Hirudin variant-1	refludan	DRUGBANK	DB00001	C287H440N80O110S6	biologic	B01AE02	138068-37-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
3	4	108447	2147	-	F2	PT\|RPRGL2\|THPH1	9606	Homo sapiens	inhibitor	target	Fabrizio MC (2001)	11467439	171736	1	Lepirudin	Lepirudin recombinant\|Hirudin variant-1	refludan	DRUGBANK	DB00001	C287H440N80O110S6	biologic	B01AE02	138068-37-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
4	5	108447	2147	-	F2	PT\|RPRGL2\|THPH1	9606	Homo sapiens	inhibitor	target	Turpie AG (1999)	10505536	171735	1	Lepirudin	Lepirudin recombinant\|Hirudin variant-1	refludan	DRUGBANK	DB00001	C287H440N80O110S6	biologic	B01AE02	138068-37-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
5	6	108447	2147	-	F2	PT\|RPRGL2\|THPH1	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1	Lepirudin	Lepirudin recombinant\|Hirudin variant-1	refludan	DRUGBANK	DB00001	C287H440N80O110S6	biologic	B01AE02	138068-37-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
6	7	108507	2213	RP11-474I16.2	FCGR2B	CD32\|CD32B\|FCG2\|FCGR2\|IGFR2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer\|Ctuximab\|Cetuximab\|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
7	8	108507	2213	RP11-474I16.2	FCGR2B	CD32\|CD32B\|FCG2\|FCGR2\|IGFR2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer\|Ctuximab\|Cetuximab\|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
8	9	107177	716	-	C1S	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer\|Ctuximab\|Cetuximab\|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
9	10	107177	716	-	C1S	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2	Cetuximab	Immunoglobulin G 1 (human-mouse monoclonal C 225 gamma 1 - chain anti-human epidermal growt factor receptor), disulfide wit human-mouse monoclonal C 225 kappa - chain, dimer\|Ctuximab\|Cetuximab\|Cetuximabum	erbitux	DRUGBANK	DB00002	C6484H10042N1732O2023S36	biologic	L01XC06	205923-56-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-

Last rows

	#BioGRID Chemical Interaction ID	BioGRID Gene ID	Entrez Gene ID	Systematic Name	Official Symbol	Synonyms	Organism ID	Organism	Action	Interaction Type	Author	Pubmed ID	BioGRID Publication ID	BioGRID Chemical ID	Chemical Name	Chemical Synonyms	Chemical Brands	Chemical Source	Chemical Source ID	Molecular Formula	Chemical Type	ATC Codes	CAS Number	Curated By	Method	Method Description	Related BioGRID Gene ID	Related Entrez Gene ID	Related Systematic Name	Related Official Symbol	Related Synonyms	Related Organism ID	Related Organism	Related Type	Notes	InChIKey
29083	29824	111464	5468	-	PPARG	CIMT1\|GLM1\|NR1C3\|PPARG1\|PPARG2\|PPARgamma	9606	Homo sapiens	unknown	target	Desai RC (2003)	12873517	224920	9745	(5S)-5-[3-[3-(4-Phenoxyphenoxy)propoxy]phenyl]-1,3-thiazolidine-2,4-dione	BDBM50131502	-	PUBCHEM	54581270	C24H21NO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BTMVNTBNPIYHBM-QFIPXVFZSA-N
29084	29825	111464	5468	-	PPARG	CIMT1\|GLM1\|NR1C3\|PPARG1\|PPARG2\|PPARgamma	9606	Homo sapiens	unknown	target	Ebdrup S (2003)	12672231	170525	6481	Ragaglitazar	NN-622\|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID\|2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YL-ETHOXY)-PHENYL]-PROPIONIC ACID(-) DRF 2725\|Q27088511\|DRF-2725\|2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YL-ETHOXY)-PHENYL]-PROPIONIC ACID\|NNC-61-0029\|(2S)-2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YLETHOXY)PHENYL]PROPANOIC ACID\|1NYX\|DRF\|(-)-DRF-2725\|DRF2725\|(S)-2-ETHOXY-3-[4-(2-PHENOXAZIN-10-YL-ETHOXY)-PHENYL]-PROPIONIC ACID\|DB07675\|RAGAGLITAZAR\|GTPL2664\|BDBM50109551	-	DRUGBANK	DB07675	C25H25NO5	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	WMUIIGVAWPWQAW-DEOSSOPVSA-N
29085	29826	111464	5468	-	PPARG	CIMT1\|GLM1\|NR1C3\|PPARG1\|PPARG2\|PPARgamma	9606	Homo sapiens	unknown	target	Santini C (2003)	12657263	224921	9746	2-[3-Chloro-4-[3-[4-[(Z)-C-ethyl-N-hydroxycarbonimidoyl]-3-hydroxy-2-propylphenoxy]propylsulfanyl]phenyl]acetic acid	3-CHLORO-4-[3-[2-PROPYL-3-HYDROXY-4-[1-(HYDROXYIMINO)PROPYL]PHENOXY]PROPYLTHIO]BENZENEACETIC ACID\|BDBM50126019	-	PUBCHEM	136088972	C23H28ClNO5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JLVVAYSKHQLKES-PLRJNAJWSA-N
29086	29827	111464	5468	-	PPARG	CIMT1\|GLM1\|NR1C3\|PPARG1\|PPARG2\|PPARgamma	9606	Homo sapiens	unknown	target	Santini C (2003)	12657263	224921	9747	Benzeneacetic acid, 3-chloro-4-((3-((3-phenyl-7-propyl-6-benzofuranyl)oxy)propyl)thio)-	UNII-O937X0Z5EM\|{3-CHLORO-4-[3-(3-PHENYL-7-PROPYL-BENZOFURAN-6-YLOXY)-PROPYLSULFANYL]-PHENYL}-ACETIC ACID\|BENZENEACETIC ACID, 3-CHLORO-4-((3-((3-PHENYL-7-PROPYL-6-BENZOFURANYL)OXY)PROPYL)THIO)-\|3-CHLORO-4-(3-(3-PHENYL-7-PROPYLBENZOFURAN-6-YLOXY)PROPYLTHIO)-PHENYLACETIC ACID\|L-796,449\|L796449\|O937X0Z5EM\|2-[3-CHLORO-4-[3-[(3-PHENYL-7-PROPYL-1-BENZOFURAN-6-YL)OXY]PROPYLSULFANYL]PHENYL]ACETIC ACID\|L-796449\|L 796449\|Q27078434\|{3-CHLORO-4-[3-(3-PHENYL-7-PROPYL-BENZOFURAN-6-YLOXY)-PROPYLSULFANYL]-PHENYL}-ACETIC ACID(L-796449)\|GTPL2689\|194608-80-5\|BDBM50085040	-	PUBCHEM	9891946	C28H27ClO4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KAPDPGZDHUCILF-UHFFFAOYSA-N
29087	29828	111464	5468	-	PPARG	CIMT1\|GLM1\|NR1C3\|PPARG1\|PPARG2\|PPARgamma	9606	Homo sapiens	unknown	target	Brooks DA (2001)	11405642	224922	9748	5-[[4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione	AD 5061\|AD-5061\|BM-131246\|AD 7057\|AD5061\|5-{4-[2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHOXY]BENZYL}-2,4-THIAZOLIDINEDIONE\|GTPL2663\|5-({4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL}METHYL)-1,3-THIAZOLIDINE-2,4-DIONE\|Q27074311\|HY-101758\|AD-7057\|CS-6704\|5-[[4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL]METHYL]-1,3-THIAZOLIDINE-2,4-DIONE\|AD7057\|BDBM50064451	-	PUBCHEM	9953271	C22H20N2O4S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	GUTCYOKMCPFRGH-UHFFFAOYSA-N
29088	29829	111464	5468	-	PPARG	CIMT1\|GLM1\|NR1C3\|PPARG1\|PPARG2\|PPARgamma	9606	Homo sapiens	unknown	target	Brooks DA (2001)	11405642	224922	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion\|Rosiglitazon\|Rosiglitazonum\|Rosiglitazone\|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione\|Rosiglitazona\|BDBM50030474	phl-rosiglitazone\|avandaryl\|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03\|A10BG02\|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N
29089	29830	109943	3741	-	KCNA5	ATFB7\|HCK1\|HK2\|HPCN1\|KV1.5\|PCN1	9606	Homo sapiens	unknown	target	Coghlan MJ (2001)	11356099	224923	9575	N-[3-(4-Ethyl-benzenesulfonylamino)-2-hydroxy-indan-5-yl]-3-methoxy-benzamide	N-((2R,3R)-3-(4-ETHYLPHENYLSULFONAMIDO)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-5-YL)-3-METHOXYBENZAMIDE\|N-[3-(4-ETHYL-BENZENESULFONYLAMINO)-2-HYDROXY-INDAN-5-YL]-3-METHOXY-BENZAMIDE\|BDBM50099581	-	PUBCHEM	17748224	C25H26N2O5S	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	KCRNOVULDSNKBZ-DNQXCXABSA-N
29090	29831	109941	3738	RP11-284N8.3	KCNA3	HGK5\|HLK3\|HPCN3\|HUKIII\|KV1.3\|MK3\|PCN3	9606	Homo sapiens	unknown	target	Coghlan MJ (2001)	11356099	224923	9749	Methyl (1S,2S,3S,4R,5S,6S,8R,12S,15S,16S,22R,23R,24S)-3,4,24-triacetyloxy-22-[(1R)-1-acetyloxyethyl]-2,5,15-trimethyl-9-methylidene-19-oxo-23-prop-1-en-2-yloxy-7,20-dioxahexacyclo[13.9.0.02,12.05,11.06,8.016,22]tetracos-17-ene-6-carboxylate	5-ISOPROPENYLOXY-1B,3A,10B-TRIMETHYL-2,3-DI(METHYLCARBONYLOXY)-5A-(1-METHYLCARBONYLOXYETHYL)-14-METHYLENE-1A-METHYLOXYCARBONYL-8-OXO-1A,1B,2,3,3A,3B,4,5,5A,6,8,10A,10B,11,12,12A,12B,13,14,14A-ICOSAHYDROOXIRENO[3'',2'':7,8]CHRYSENO[2,1-C]OXEPIN-4-YLACETA\|BDBM50099583	-	PUBCHEM	44290049	C41H54O14	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VBCYJMDXVYKTHI-SMYFPHPLSA-N
29091	29832	111464	5468	-	PPARG	CIMT1\|GLM1\|NR1C3\|PPARG1\|PPARG2\|PPARgamma	9606	Homo sapiens	unknown	target	Henke BR (1999)	10612594	224924	9750	2-Phenyl-3-(4-methoxyphenethyl)-1H-indole-5-acetic acid	{3-[2-(4-METHOXY-PHENYL)-ETHYL]-2-PHENYL-1H-INDOL-5-YL}-ACETIC ACID(GW 0207)\|2-PHENYL-3-(4-METHOXYPHENETHYL)-1H-INDOLE-5-ACETIC ACID\|258345-12-9\|2-(3-(4-METHOXYPHENETHYL)-2-PHENYL-1H-INDOL-5-YL)ACETIC ACID\|2-[3-[2-(4-METHOXYPHENYL)ETHYL]-2-PHENYL-1H-INDOL-5-YL]ACETIC ACID\|{3-[2-(4-METHOXY-PHENYL)-ETHYL]-2-PHENYL-1H-INDOL-5-YL}-ACETIC ACID\|GW0207\|BDBM50083625	-	PUBCHEM	10068664	C25H23NO3	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YZLHLVJLTOPOHC-UHFFFAOYSA-N
29092	29833	111464	5468	-	PPARG	CIMT1\|GLM1\|NR1C3\|PPARG1\|PPARG2\|PPARgamma	9606	Homo sapiens	unknown	target	Parks DJ (1998)	9934490	224925	404	Rosiglitazone	(RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion\|Rosiglitazon\|Rosiglitazonum\|Rosiglitazone\|()-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione\|Rosiglitazona\|BDBM50030474	phl-rosiglitazone\|avandaryl\|av	DRUGBANK	DB00412	C18H19N3O3S	small molecule	A10BD03\|A10BG02\|A10BD04	122320-73-4	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	YASAKCUCGLMORW-UHFFFAOYNA-N

Overview

Variables

Interactions

Correlations

Pearson's r

Spearman's ρ

Kendall's τ

Phik (φk)

Cramér's V (φc)

Missing values

Sample

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Last rows